7 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Renal Tubular Defects ... Thick ascending loop ... of Henle Gitelman ... #Localization #Nephron ... #Defects #Pathophysiology
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
NSAIDS and their effects ... modify immune function ... reabsorption in Proximal, loop ... KidneyDisease #nephrology #Effects ... #pathophysiology
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Differential Diagnosis Algorithm ... Urine Mg > 10g • Loop ... Hypercalcemia-PTH effect ... nephrocalcinosis (FHHNC) • Gitelman's ... ab • Genetics defects
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
Physiological Effects ... Altered Renal Function ... excretion in distal nephron ... Nonhemodynamically mediated effects ... AngiotensinII #Pathophysiology
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... Remote use of loop ... Vomiting/nasogastric suction ... Bartter syndrome, Gitelman ... mineralocorticoid-like effect
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
vomiting/ nasogastric suction ... • Thiazide or loop ... tubule diuretic effect ... tubule reabsorptive defect ... furosemide-like lesion) • Gitelman
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... Remote use of loop ... Vomiting/nasogastric suction ... Bartter syndrome, Gitelman ... mineralocorticoid-like effect