52 results
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Diuretics (e.g. mannitol ... ) 3) Loop Diuretics ... HCTZ) 5) Potassium-sparing ... spironolactone) #Pathophysiology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... Osmotic agents (mannitol ... urearetics) 3) Loop ... Adenosine #Nephron #Pathophysiology
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
diuretics (e.g. mannitol ... ) 3) Loop diuretic ... Metolazone) 5) Potassium-sparing
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Normal Acid-Base: Low ... • HTN Absent: Loop ... Differential #Diagnosis #Algorithm ... #causes #potassium
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
empagliflozin LOOP ... Chlorthalidone POTASSIUM-SPARING ... DIURETICS • Mannitol
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #pathophysiology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Algorithm for patients ... the basis of the potassium-to-creatinine ... High Urine Cl - Loop ... hypokalemia #urine #potassium ... #differential #algorithm
Diagnostic Approach to Hyponatremia
Box A:
 • Normo/hyperosmolar Hyponatremia: Glucose, Mannitol, Glycine, Contrast media, Maltose
 • Pseudohyponatremia:
Hyponatremia: Glucose, Mannitol ... Primary Polydipsia, Low ... Hyponatremia #Diagnosis #Algorithm
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Differential Diagnosis Algorithm ... vomiting) • Low ... Differential #Diagnosis #Algorithm ... #nephrology #low ... #potassium
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Mechanisms of Loop ... Panel A, loop diuretics ... binding to sodium–potassium–chloride ... #Pathophysiology