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antinuclear antibody testing antibodies cytoplasmic management nuclear algorithm autoimmune classification comparison headache hematology hodgkins inflammatory lymphoma mnemonic myopathies myopathy myositis
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Testing - Nuclear and ... phenomenon, SjS, cancer ... ARUPConsult @ARUPLabs #ANA ... #differential # ... diagnosis #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... or scleroderma (SSc ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
phenomenon, SjS, cancer ... • Fibrillarin, RNA ... ARUPConsult @ARUPLabs #ANA ... #differential # ... diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
: The ANA patterns ... Patterns and Associated ... or scleroderma (SSc ... #patterns #rheumatology ... #diagnosis #differential
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Associated Features: Cancer-associated ... : Proximal and distal ... Inflammatory #Myopathies #differential ... #diagnosis #comparison ... #rheumatology #
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
Diagnosis Algorithm ... PHANTOMS): • Pattern ... syndrome, history of cancer ... Systemic symptoms and ... conditions: • Stroke, carotid
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
coagulopathy) • CBC w differential ... BNP, troponin if concern ... o infection • Echocardiogram ... • IF staining patterns ... Renal #Syndromes #differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Anterior mediastinal mass ... X-ray (Mediastinal mass ... lymph node biopsy (diagnostic ... Immunohistochemical studies (to differentiate ... Hodgkins #lymphoma #diagnosis
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Testing Cytoplasmic Patterns ... ARUPConsult @ARUPLabs #ANA ... #Cytoplasmic #Patterns ... #differential # ... diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... RP-ILD), dermato-rheumatologic ... • Anti-TIF1 (cancer-associated ... pattern of muscle ... #differential #
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