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ana antinuclear antibody management testing antibodies cytoplasmic mnemonic nuclear pulmonary treatment adultonset algorithm autoimmune cavitary cavity classification comparison disease headache
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
and Cytoplasmic Patterns ... Nuclear Patterns ... phenomenon, SjS, cancer ... #differential # ... diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Testing - Nuclear Patterns ... Homogeneous pattern ... phenomenon, SjS, cancer ... #differential # ... diagnosis #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... or scleroderma (SSc ... Antibodies #ANA #patterns ... #rheumatology # ... diagnosis #differential
CAVITY – a useful mnemonic for the causes of a cavitating lung mass. C = cancer
cavitating lung mass ... C = cancer - ... most frequently SCC ... bronchogenic cyst #Diagnosis ... Cavitary #Lesions #Differential
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Associated Features: Cancer-associated ... Associated Features: Diagnosis ... Inflammatory #Myopathies #differential ... #diagnosis #comparison ... #rheumatology #
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
to Headaches - Differential ... Diagnosis Algorithm ... PHANTOMS): • Pattern ... syndrome, history of cancer ... conditions: • Stroke, carotid
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
significant • Pattern ... : The ANA patterns ... or scleroderma (SSc ... #rheumatology # ... diagnosis #differential
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... hemopathies, solid cancers ... Complications: MAS ... management #treatment #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
coagulopathy) • CBC w differential ... BNP, troponin if concern ... o infection • Echocardiogram ... • IF staining patterns ... Renal #Syndromes #differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Anterior mediastinal mass ... X-ray (Mediastinal mass ... lymph node biopsy (diagnostic ... Immunohistochemical studies (to differentiate ... Hodgkins #lymphoma #diagnosis
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