18 results
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
ejection fraction, treatment ... hospitalization for the management ... Cardiology #EBM #VisualAbstract ... #Trial
How to use C-reactive protein (CRP)- Review https://ep.bmj.com/content/early/2018/07/19/archdischild-2018-315079

 - An CRP alone cannot be used to
Serial normal CRPs ... - A single CRP measurement ... guide intial treatment ... CReactiveProtein #VisualAbstract
The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an
The WOMAN Trial ... Antifibrinolytic Trial ... tranexamic acid for the treatment ... resuscitation, management ... PostPartum #Hemorrhage #VisualAbstract
Clinic, Home, and Ambulatory Blood Pressure Measurements - Strengths and Weaknesses
(via https://twitter.com/JACCJournals/status/1088104323354185730 )

Clinic Measurements:
• BP measured
Blood Pressure Measurements ... used to guide treatment ... large outcome trials ... only 1 or 2 BP measurements ... Home #Ambulatory #Management
Hyperacute Hypoxemia - Workup and Management
Differential Diagnosis: Aspiration, Flash Pulmonary Edema, Mucous Plugging, Bronchospasm, Pulmonary Embolism,
Hypoxemia - Workup and Management ... Differential Diagnosis ... CXR, CTA Chest, Echocardiogram ... Workup #diagnosis #Management ... #treatment #criticalcare
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
syncope (ruling out differential ... further guide management ... orthostatic vital sign measurements ... The treatment strategy
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
Presence of pulmonary arterial ... Transthoracic echocardiogram ... ventricular size, Right atrial ... pressure < 15mmHg TREATMENT ... Hypertension #diagnosis #management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Disease Clinical triad ... fraction < 20% Differential ... Disease #diagnosis #management ... #treatment #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Triggers: ATRA ... treatment Pathophysiology ... initiation • Differential ... Renal Failure Treatment ... APML #diagnosis #management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Features: • Triad ... Rhabdomyolysis #Differential ... #Diagnosis #Management