30 results
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... Hyperviscosity Syndrome ... • Dyspnea at rest ... Progressive decline in mental ... #differential #
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Medium and large ... (Clinical Dx). ... Behcet disease) Differential ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... capillary leak syndrome ... • Schnitzler syndrome ... #Diagnosis #hematology ... #oncology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... life-threatening Differential ... Clinical DX: - ... Bedside: ice pack test ... /Edrophonium test
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
Behcet's Syndrome ... Abnormal pathergy test ... Most Common Clinical ... oligoarticular, medium-large ... Diagnosis #criteria #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... initiation • Differential ... Renal Failure Treatment ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytes • Median ... immunophenotype Clinical ... transformation) Treatment ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
Hearing Loss - Differential ... disruption ○ Otitis media ... II ○ Susac’s syndrome ... Hearing #Loss #Differential ... #Diagnosis #otology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... Liver function tests ... Treatment: • Corticosteroids ... #Rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... Orange or Hep C Clinical ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology