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diagnosis differential management algorithm cancer clinical dermatology hematology causes treatment table pharmacology leukemia skin chemotherapy classification comparison physicalexam syndrome video
Melanoma Pathogenesis Environmental exposure (UV light) + genetic susceptibility (CDKN2A, CDK4, MC1R, BRAF, p16/ARF genes) → accumulation
Melanoma Pathogenesis ... Pathophysiology #Oncology ... #Melanoma #Carcinogenesis
Melanoma Treatment Algorithm Resectable vs Inoperable Disease Matthew Ho, MD PhD @MatthewHoMD and Aakash Desai, MD @ADesaiMD #Melanoma #Treatment
Melanoma Treatment ... @ADesaiMD #Melanoma ... #dermatology #oncology
Tumor markers in clinical practice Colorectal - CEA Hepatocellular - AFP Pancreatic - CA 19-9 Ovarian - CA 125 Breast -
- NSE, proGRP Melanoma ... laboratory #diagnosis #oncology
Melanoma tumour progression (based on the Clark model) - Benign melanocytic nevi: controlled proliferation of normal
Melanoma tumour ... continuous atypia (melanoma ... Pathophysiology #Oncology ... #Melanoma #Clark
Checkpoint inhibitors and indications Anti CTLA-4 antibody: • Ipilimumab: Malignant melanoma, Renal cell cancer Anti-PD-1 antibody: • Nivolumab:
Ipilimumab: Malignant melanoma ... Nivolumab: Malignant melanoma ... #indications #oncology
Types of Melanoma Superficial Spreading • Most common form • Often develops in previously benign mole •
Types of Melanoma ... • 70% of all melanomas ... 10-15% of all melanomas ... common type of melanoma ... #Melanoma #Types
Acral Lentiginous Melanoma (involving nail) While acral lentinginous melenoma is often seen anywhere on the palms, soles,
Acral Lentiginous Melanoma ... acral lentinginous melenoma ... clue that this is melanoma ... #Lentiginous #Melanoma
Melanoma - Clinical subtypes - Superficial spreading melanoma (70%) - Nodular melanoma (15%) - Lentigo maligna
Melanoma - Clinical ... Superficial spreading melanoma ... ) - Nodular melanoma ... Lentigo maligna melanoma ... #Diagnosis #Melanoma
Skin Cancer Overview - Basal Cell, Squamous Cell and Melanoma #Skin #Cancer #Basal #Squamous #Melanoma #Dermatology #Diagnosis
Squamous Cell and Melanoma ... Basal #Squamous #Melanoma
ABCDEs of Skin Cancer - Melanoma A - Asymmetry B - Border C - Color D - Diameter E - Evolving #Diagnosis
Skin Cancer - Melanoma ... #ABCs #ABCDEs #Melanoma
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