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diagnosis differential management nephrology algorithm causes hematology hypokalemia oncology vasculitis aids apml associated behcet cardiorenal dementia differentiation disease disorder encephalopathy
Mechanisms of nephron damage in cardiorenal syndrome • Increased renal interstitial pressure • Hypoperfusion • Reduced
in cardiorenal syndrome ... hypertrophy • Sodium ... #cardiorenal #syndrome ... #Mechanisms #pathophysiology ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
anemia) • G-CSF ... • Refeeding syndrome ... vomiting) • Low ... Diagnosis #Algorithm #nephrology ... #low #potassium
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... • Gitelman's syndrome ... alkalosis • Normal or low ... • Bartter syndrome ... #management #pathophysiology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... occlusion, Budd-Chiari syndrome ... tests in Behcet syndrome ... adenopathy (PFAPA) syndrome ... hyperimmunoglobulin D syndrome
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Encephalopathy Syndrome ... Clinico-Radiological Syndrome ... syndrome by 24 ... Paraneoplastic syndrome ... Encephalopathy #Syndrome
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... age 70 years Symptoms ... (CML) • Felty Syndrome ... Myelodysplastic Syndrome
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... sepsis), PE, DAH, CHF ... Differentiation #Syndrome
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Mucocutaneous lymph node syndrome ... VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... • Complement (Low ... #classification
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Cirrhosis, Nephrotic Syndrome ... , Chronic Renal ... Alcohol MH/CCF ... diagnosis #causes #nephrology ... #sodium #low
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Mucocutaneous lymph node syndrome ... • Progressive symptoms ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
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