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rheumatology lupus systemic cardiology syndrome activation admissions admitting cardiomyopathy cerebritis classification cns comparison criticalcare cryoglobulinemia cryoglobulins dermatology druginduced endocarditis hemophagocytic
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... life-threatening • Treatment ... #Diagnosis #Management ... #Summary #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
- Summary Antinuclear ... severe disease Treatment ... #SLE #Summary # ... diagnosis #rheumatology ... #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... Lumbar Puncture, EEG ... Treatment: ... #rheumatology # ... #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Systemic Lupus Erythematosus ... life-threatening • Treatment ... Usual therapeutic management ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Systemic lupus erythematosus ... [SLE], AOSD) • ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Muscle Toxicity - Summary ... systemic lupus erythematosus ... (SLE), polymyositis ... (SAMS-CI) • EMG ... #management #treatment
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... diseases: - 10% SLE ... Labs/Diagnosis: ... systemic lupus erythematosus ... (SLE), rheumatoid
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Autoimmune diseases: SLE ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Admitting in the ICU - Checklist VITALS: If bad, stop and go see the patient immediately; you
Admitting in the ICU - Checklist ... bad, stop and go see ... esp in work-up/management ... note, discharge summary ... #diagnosis #workup
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Cardiomyopathy - Summary ... Differential Diagnosis ... orthopnea, PND, LE ... Cardiomyopathy #diagnosis ... #treatment
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