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differential anemia algorithm causes microscopy rbc workup nomenclature basics bloodcell bloodsmear cell cryofibrinogenemia dermatology dyspmorphic electrophoresis enlarged extravascular hemolysis indications
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
#RedBloodCell #Morphology ... #Morphologies #Key ... #Atlas #Microscopy ... #Pathology #Hematology ... #Diagnosis #Dyspmorphic
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Blood Cell (RBC) Morphology ... Atlas • Microcytic ... spherocytosis, Hemolytic ... #Atlas #key #diagnosis ... #differential #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... for Hemolysis - ... lymphoproliferative disorders ... #differential #diagnosis ... #hematology #anemia
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
and laboratory diagnosis ... , not a morphologic ... count, D-dimer, egg ... #anemia #Hematology ... #Pathology #Smear
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Unstable hemoglobin disorders ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential Diagnosis ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... other reproducible morphologic ... Consider RBC membrane disorder ... #Differential #Diagnosis ... Algorithm #workup #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential Diagnosis ... iron deficiency, hemolysis ... Chronic inflammatory disorders ... (e.g. autoimmune ... #Causes #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... acute blood loss, hemolysis ... (BM) ablative disorders ... of substrate (e.g ... #Workup #Hematology
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
amyloidosis, or related disorder ... possible malignancy (e.g ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology ... #Diagnosis
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