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differential liver transaminitis algorithm aih arthritis autoimmune bloodcell chemistry dili disease druginduced function hepatocellular interpretation laboratory management microscopy nomenclature patterns
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... , HBV, HCV, HEV, ... . ascites), Chronic ... hepatitis fibrosis ... #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... normal - Infection (EBV ... 5-10x normal - Chronic ... #hepatology #LFTs ... #differential #diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Function Tests (LFTs ... Cirrhosis • Chronic ... Viral Hepatitis ... Drug-induced liver injury ... #hepatology #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... • Infections: Hepatitis ... #hepatology #algorithm ... Transaminitis #LFTs ... #hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... , HBV, HCV, HEV, ... > 2 • NASH, Chronic ... : > 3 • Chronic ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... : > 3 • Chronic ... liver #chemistry #diagnosis ... #differential #Hepatology ... transaminitis #LFTs
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Blood Cell (RBC) Morphology ... Chemotherapy (e.g ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... - Symptoms of chronic ... pattern of liver injury ... , AIH diagnosis ... #Management #Hepatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
IgM) levels • Hepatitis ... Screening Tests for Chronic ... function tests (LFTs ... (to support a diagnosis ... arthritis) • Hepatitis
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