16 results
4T Score for Heparin-Induced Thrombocytopenia

Interpretation of the 4T score:
0-3 points:  Low probability (<<1%)
  -
Thrombocytopenia ... - No further workup ... HeparinInduced #Thrombocytopenia ... #Diagnosis #Criteria ... #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Blood Cell (RBC) Morphology ... Atlas • Microcytic ... Thrombotic idiopathic thrombocytopenia ... #Atlas #key #diagnosis ... #differential #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... function test, ANA (e.g ... #Causes #Workup ... #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... TMA: Unexplained thrombocytopenia ... hemoglobin/hemosiderin, Hepatic ... hemosiderin • PT/aPTT normal ... Management #Algorithm #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
- Differential Diagnosis ... Algorithm Thrombocytopenia ... Destruction • Abnormal ... Rare • Drugs (e.g ... Algorithm #Causes #Hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
count and platelet morphology ... Gplb receptor • Thrombcytopenia ... platelet count and morphology ... Platelet #disorders #hematology ... #differential #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
dysfunction (25%) • Hepatic ... deficiency) • HIT: Heparin-PF4 ... 100mg/dL) - Heparin ... #Coagulation #diagnosis ... treatment #management #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... other reproducible morphologic ... Schistocytes, thrombocytopenia ... #Algorithm #workup ... #hematology #testing
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Blood Cell (RBC) Morphology ... Chemotherapy (e.g ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... . heparin contamination ... thrombin inhibitors, heparin ... amyloidosis #Abnormal ... #differential #hematology