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differential anemia management nephrology rheumatology treatment acute algorithm antibodies arthritis associations autoantibodies bloodcell causes disease diseases extravascular fever hemolysis hyperkalemia
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... Chemotherapy (e.g ... #Morphology #differential ... #diagnosis #hematology ... #microscopy #atlas
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... #Morphology #Atlas ... #key #diagnosis ... #differential #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... • Intrinsic RBC ... deficiencies (e.g ... #hematology #anemia
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
and laboratory diagnosis ... , not a morphologic ... count, D-dimer, egg ... #anemia #Hematology ... Pathology #Smear #Microscopy
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... acute blood loss, hemolysis ... of substrate (e.g ... Anemia #Algorithm #Diagnosis ... #Workup #Hematology
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
dialysis indication (e.g ... Nephrotoxic drugs (e.g ... Assess UA w/ microscopy ... for WBCs, RBCs, ... KidneyInjury #simplified #workup
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
biliary cirrhosis (PBC ... - Vasculitis, e.g ... - Vasculitis, e.g ... Microscopic polyangiitis ... Associations #diseases #diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... fever - ACS, AKI ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), MPA (microscopic ... EGPA) • Renal: (AKI ... mononeuritis multiplex WORKUP ... recent DAN) • EMG ... gross hematuria, RBC
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
injury, ischemia, hemolysis ... , RTA Type IV, AI ... reabsorption) Workup ... draw, ↑↑Plts or ↑↑WBC ... heparinized tube) • ECG
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