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differential algorithm anemia causes rheumatology nephrology elevatedmcv hemolytic key macrocytosis management microcytic oncology pathology syndromes acute aki antibodies arthritis associations
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
) Morphology Atlas ... Lead poisoning • Macrocytic ... #Morphology #Atlas ... #key #diagnosis ... #differential #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... anemia (sometimes) Macrocytic ... Chemotherapy (e.g ... #diagnosis #hematology ... #microscopy #atlas
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... of substrate (e.g ... Anemia #Algorithm #Diagnosis ... #Workup #Hematology ... #Microcytic #Macrocytic
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Red Blood Cell (RBC ... #RedBloodCell #Morphology ... Morphologies #Key #Atlas ... #Microscopy #Pathology ... #Hematology #Diagnosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Neutrophils - Low RBC ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... • Secondary (e.g ... Polychromatic Macrocytes ... Polychromatic Macrocytes ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential Diagnosis ... Spherocytosis, G6PD, PK, HbC ... Infections Macrocytic ... aciduria, Drugs (e.g ... #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
- Differential Diagnosis ... Iron Deficiency (Eg ... Other • e.g ... #Microcytic #Anemia ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... • Intrinsic RBC ... deficiencies (e.g ... #hematology #anemia
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
biliary cirrhosis (PBC ... - Vasculitis, e.g ... - Vasculitis, e.g ... Microscopic polyangiitis ... Associations #diseases #diagnosis
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