37 results
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
and Associated Diseases ... #RedBloodCell #Morphology ... Morphologies #Key #Atlas ... #Microscopy #Pathology ... #Hematology #Diagnosis
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... Chemotherapy (e.g ... #Morphology #differential ... #diagnosis #hematology ... #microscopy #atlas
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... #Morphology #Atlas ... #key #diagnosis ... #differential #hematology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
- Vasculitis, e.g ... - Vasculitis, e.g ... Microscopic polyangiitis ... #diagnosis #table ... #rheumatology #
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... • Intrinsic RBC ... deficiencies (e.g ... #hematology #anemia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Neutrophils - Low RBC ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... other reproducible morphologic ... #Differential #Diagnosis ... #Algorithm #workup ... #hematology #testing
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (MCV): Average RBC ... of substrate (e.g ... Anemia #Algorithm #Diagnosis ... #Workup #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... function test, ANA (e.g ... #Causes #Workup ... #hematology
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
• Provoked (e.g ... - No other workup ... cancer screening, CBC ... #hematology #diagnosis ... #algorithm #hematology