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management rheumatology erythematosus lupus sle systemic bloodcell cerebritis cns differential hemeonc hemophagocytic hlh lymphohistiocytosis macrophage mas microscopy myelodysplasia myelodysplastic neurology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Syndrome (MAS) ... Classified among the secondary ... #Macrophage #Activation ... #Syndrome #Diagnosis
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Liver Disease, MDS ... Chemotherapy (e.g ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... permeability Diagnosis ... Lumbar Puncture, EEG ... APS), Secondary ... Maheswaranathan, MD
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... DDX: Rule Out Secondary ... Workup: • Complete ... #diagnosis #hematology ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... vein thrombosis Hematologic ... (C3 and C4) • ds-DNA ... Chronic B-cell activation ... Erythematosus #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... STX11, STXBP2 • Secondary ... (often termed MAS-HLH ... Syndrome) 3. ... #Management #Hematology
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