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differential anemia thromboembolism anesthesia anesthesiology blood bloodcell cardiology checklist disorders embolism embolus endocarditis eosinophil eosinophilia erythrocytosis essential et evaluation hemolytic
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
thromboembolism → Cardiac ... • Provoked (e.g ... - No other workup ... #hematology #diagnosis ... #algorithm #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... signs or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Algorithm • Sickle ... other reproducible morphologic ... aHUS, mechanical cardiac ... #Algorithm #workup ... #hematology #testing
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Blood Cell (RBC) Morphology ... Chemotherapy (e.g ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... of substrate (e.g ... #Diagnosis #Workup ... #Hematology #Microcytic
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
Polycythemia Differential Diagnosis ... Algorithm Elevated ... Hypoxia-driven: Cardiac ... Paraneoplastic (e.g ... #Algorithm #hematology
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia Causes: thrombus, fat, amniotic fluid, air/gas. Signs: hypotension, tachycardia,
unexplained loss of cardiac ... Consider thrombolysis e.g ... Embolus #Embolism #VTE ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
lethargy, hematuria, cardiac ... unless worrisome EKG ... with tetany or cardiac ... Syndrome #TLS #diagnosis ... #management #hematology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
dental procedure • Cardiac ... Hypercoagulable (APLAS ... : • New cardiac ... ↑ ESR, CRP • EKG ... #management #cardiology
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
event, follow ACC algorithm ... indicated • EKG ... Obtain EKG if: ... • <3mo since VTE ... stratification #diagnosis
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