54 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
PT - Prolonged aPTT ... PT - Prolonged aPTT ... Coagulation #Abnormal #APTT ... #Laboratory #Hematology ... #Diagnosis #Workup
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
• Provoked (e.g ... - No other workup ... screening, CBC, aPTT ... #hematology #diagnosis ... #algorithm #hematology
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
- Differential Diagnosis ... /uL Initial Workup ... iron studies, PT/aPTT ... #Algorithm #hematology ... #workup
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Evaluation and Management ... Manifestations and Management ... #Diagnosis #Management ... #Hematology #SickleCell ... Manifestations #Workup
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
#RedBloodCell #Morphology ... Morphologies #Key #Atlas ... Microscopy #Pathology #Hematology ... #Diagnosis #Dyspmorphic
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... clotting test (e.g ... PT and/or aPTT) ... #hematology #pathophysiology ... #hematology #laboratory
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management ... antiglobulin test, PT/aPTT ... hemosiderin • PT/aPTT ... #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Blood Cell (RBC) Morphology ... Atlas • Microcytic ... coagulopathy (DIC) #RBC #Morphology ... #Atlas #key #diagnosis ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Pre-analytical cause (e.g ... inhibitory drugs (e.g ... specific inhibitor (e.g ... #differential #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Nonspecific inhibitors e.g ... to one factor e.g ... inhibitory drugs e.g ... Prolonged #Causes #diagnosis ... #differential #hematology