16 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... May be 10 (eg direct ... diabetes)) #Glomerular ... #Nephrology #Diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... • Fanconi's syndrome ... • Drugs Glomerular ... polyangiitis (GPA) / microscopic ... Protein deposition (eg
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... infection • Hyaline ... #Microscopy #Atlas ... #key #diagnosis ... #nephrology #casts
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
hematuria and/or proteinuria ... the patient have glomerular ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology ... #Diagnosis
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... disease - Alport syndrome ... pain hematuria syndrome ... - RBC casts → Diagnostic ... - Proteinuria
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
hemolytic-uremic syndrome ... arbitrarily defined as urine ... #glomerular #proteinuria ... #nephrotic #syndrome ... #nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... polyangiitis, Microscopic ... sclerosis • Anti-Glomerular ... • Urinalysis (proteinuria ... #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... RBC casts, +/- proteinuria ... formation along glomerular ... anti-phospholipid syndrome ... #diagnosis #renal
Hepatorenal Syndrome Diagnosis
 • ↑ in serum Cr of ≥ 0.3mg/dL above baseline
Hepatorenal Syndrome ... Diagnosis • ↑ ... liver disease (e.g ... (including no proteinuria ... #nephrology #criteria
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... Acellular Casts • Hyaline ... colored compounds (e.g ... #Microscopy #nephrology ... interpretation #diagnosis