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differential hematology management disease treatment workup causes erythematosus lupus systemic abnormal ana anemia antinuclear autoantibodies infectiousdiseases microscopy myositis neurology pathology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Blood Cell (RBC) Morphology ... Atlas • Microcytic ... Myelodysplastic syndrome ... #Atlas #key #diagnosis ... #differential #hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- Vasculitis, e.g ... - Vasculitis, e.g ... #diagnosis #table ... #rheumatology # ... antibodies
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific Antibodies ... Anti-Synthetase Syndrome ... #MSAs #clinical ... #diagnosis #rheumatology ... #table
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Blood Cell (RBC) Morphology ... Chemotherapy (e.g ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Increased Requirement (e.g ... B12 - Anti-IF Antibodies ... B12 - Anti-IF Antibodies ... Myelodysplastic Syndromes
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
Behcet's Syndrome ... - Diagnosis Diagnostic ... test Most Common Clinical ... #disease #Diagnosis ... #criteria #rheumatology
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
50 years in men Diagnosis ... : • Based on clinical ... serologic, and EMG ... - 1st line: ... - Improves clinical
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Sensitive Antibodies ... Donath-Landsteiner Antibodies ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... hemolytic #anemia #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... prolong the aPTT alone ... antiphospholipid antibodies ... antiphospholipid antibodies ... Prolonged #Causes #diagnosis
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