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management erythematosus systemic neurology signs sle symptoms treatment activation ana antinuclear aspergillus autoantibodies autoimmune cerebritis cfs classification cryoglobulinemia cryoglobulins dermatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Lumbar Puncture, EEG ... #neurology #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... nervous system (CNS ... SJIA], systemic lupus ... #Diagnosis #Management ... #Hematology #Rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... (e.g. oculomotor ... pain • Extra-CNS ... disorders (Systemic lupus ... Manifestations #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Clinical Features ... and CNS • Headache ... #Rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
-15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... Labs/Diagnosis: ... tissue disorder (e.g ... . systemic lupus ... classification #rheumatology
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
immunosuppression (eg ... HIV/AIDS, CGD) Clinical ... Rhinosinusitis, CNS ... Non-pigmented (hyaline ... sometimes have this morphology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... salivary ducts Clinical ... • 8%-27% for CNS ... tears/artificial saliva ... #Rheumatology #
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... skeleton-sacroiliac joint and spine ... : • A clinical ... antiinflammatory properties e.g ... #Rheumatology #
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... renal failure Clinical ... (e.g. incidental ... Self-limiting, chronic but stable ... skin (16-32%): lupus
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