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differential oncology anemia agglutinin allergy aplastic bilaterality brownsequard chronic comparison deficit disease distribution hemolysis hemolytic immunology leukemia loss lymphocytic management
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
life Causes and clinical ... Disorientation, vertigo Diagnostic ... test, TempTest ... neutrophils and eosinophils ... #diagnosis #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... Viral Infection Clinical ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Autoimmune: Warm AIHA, Cold ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell ... Laboratory Tests ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Orange or Hep C Clinical ... Diagnosis: • ... • Richter’s Syndrome ... workup #oncology #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... anemia due to cold ... Episodic angioedema+eosinophilia ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Principal patterns of loss of sensation. (a) Thalamic lesion: sensory loss throughout opposite side (rare).
Brown—Séquard syndrome ... lesion: loss of all ... #Diagnosis #Neurology ... GrepMed Recommended Text ... Comprehensive Review in Clinical
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... Anticonvulsants - Gold ... - Hepatitis, eosinophilic ... Anemia #oncology #hematology ... #diagnosis #management
Pathergy Summary Overview What is pathergy? Pathergy is an exaggerated skin injury occurring after minor trauma such as
(PG) • Sweet syndrome ... myeloid leukemia (CML ... interferon-alpha • Atypical eosinophilic ... #Pathergy #diagnosis ... allergy #immunology #dermatology
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