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hematology differential oncology hemophagocytic hlh lymphohistiocytosis management rheumatology agglutinin anemia bleeding chronic classification cold disorders features hemeonc hemolytic history leukemia
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. Affects
Kawasaki Disease ... #Kawasaki #Disease ... #Features #Signs ... #Symptoms #Diagnosis ... #Peds #Pediatrics
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... abdominal pain • Kawasaki ... • Cogan Syndrome ... Presentation - Systemic Symptoms ... purpura: strong sign
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Diagnosis: • ... cells can indicate disease ... • Richter’s Syndrome
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... malignancies -> CLL ... hemolytic #anemia #hematology ... #diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... CRP GCA (Giant Cell ... • Check: HBV Kawasaki ... • Progressive symptoms
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Heavy Chain disease ... Autoimmunity: • -MM/WM: Vasculitis ... Sneddon-Wilkinson disease ... #Differential #Diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Episcleritis Signs ... and Symptoms: ... Leukocytoclastic vasculitis ... #diagnosis #dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... : HLH signs and ... symptoms can mimic ... Low or absent NK cell
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
von Willebrand disease ... relatives (if all ... Marfan syndrome, ... Disorders #History #peds ... #pediatrics #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
with the HLH syndrome ... ▪ Autoimmune diseases ... Presentation • Common Signs ... and Symptoms: ... #Management #Hematology
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