19 results
Morphology and Descriptions of Fungal Infections with Hyphae or Pseudohyphae in Tissues
Yeasts with Pseudohyphae: 
 •
other hyaline fungi ... Mucorales genera ... Consistent with Mucorales ... with dematiaceous fungi ... septations #pathology #atlas
Microorganisms Responsible for Infective Endocarditis

Native valves:
 - Streptococcus viridans 
 - Enterococci 
 - Other streptococci
Gram-negative bacilli - Fungi ... Histoplasma) - Culture ... Gram-negative bacilli - Fungi ... streptococci - Culture
Important Fungal Stains
Mycology Lab:
 • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
preparation from culture ... cell response to fungi ... doesn't stain most fungi ... Aspergillus spp. and the Mucorales ... staining #diagnosis #fungi
Morphology and Descriptions of Endemic Fungal Infections with Yeasts in Tissues
Broad-based budding yeasts:
 • Description: Broad-based
other hyaline fungi ... Mucorales genera ... Consistent with Mucorales ... yeasts #fungal #fungi ... morphology #pathology #atlas
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... separate blood cultures ... fastidious bacteria or fungi ... Tropheryma whipplei, Fungi ... bacteria) and 18S ( fungi
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood culture ... Tropheryma whipplei, Fungi ... identified with modern culture ... diagnosis #causes #culture
Common Fungal Pathology 
 • Candida - Small yeast intermingled with pseudohyphae
 • Aspergillosis - Septate
conidial heads • Mucorales ... microscopy #table #atlas
Endocarditis Algorithm - Infective vs Noninfective Causes
Noninfective:
 • Malignancy
 • Autoimmune disease
 • Systemic infection
Native Valve
• HACEK • Culture-negative ... Gram-negative bacilli • Fungi ... Gram-negative bacilli • Fungi
Morphology of Fungal Infections in Tissues
Fungal infections with hyphae or pseudohyphae in tissues:
 • Yeasts with
Tissues #pathology #fungi ... differential #diagnosis #atlas
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
component of many fungi ... Cryptococcus, Mucorales ... - Negative: Mucorales ... closely related fungi