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diagnosis differential complications sle adrenal erythematosus psychiatry rheumatology syndrome systemic vasculitis 21hydroxylasedeficiency 21ohd addisons agammaglobulinemia algorithm alzheimersdisease avascularnecrosis bulimianervosa cah
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
chromosome 21) Signs ... Motor dysfunction: myoclonic ... incontinence, apraxia ... AlzheimersDisease #Dementia #pathophysiology ... #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Myopathy (Also caused ... #Systemic #Lupus ... Complications #pathophysiology ... #signs #symptoms
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Fits, Hemiplegia, Ataxia ... Glomerulonephritis Myositis(5%) Blood ... erythematosus #signs ... #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... endothelium) & Decr blood ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... : Most Common Causes ... be a clue • Blood ... addisons #disease #endocrinology ... #diagnosis #signs
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms • Brain: Androgenization effects, Glucocorticoid effects,
Hydroxylase Deficiency - Signs ... and Symptoms • ... CAH-X), Increased blood ... formation, Genital atypia ... #endocrinology
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework High Altitude Pulmonary Edema: • Accumulation
10,000 ft) • Symptoms ... • Signs/Symptoms ... • Signs/Symptoms ... - The classic signs ... • Pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
go on to block blood ... Crises can be precipitated ... The underlying pathophysiology ... Crisis #Features #Signs ... #Symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Decr delivery of blood ... Livedo reticularis Blood ... inflammation tends to cause ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
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