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diagnosis complications differential sle clinical erythematosus psychiatry rheumatology syndrome systemic vasculitis acute agammaglobulinemia algorithm alzheimersdisease avascularnecrosis bulimianervosa canuliculitis centralretinalartery chronic
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
chromosome 21) Signs ... Motor dysfunction: myoclonic ... incontinence, apraxia ... AlzheimersDisease #Dementia #pathophysiology ... #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Myopathy (Also caused ... #Systemic #Lupus ... Complications #pathophysiology ... #signs #symptoms
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Fits, Hemiplegia, Ataxia ... Glomerulonephritis Myositis(5%) Blood ... erythematosus #signs ... #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... endothelium) & Decr blood ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework High Altitude Pulmonary Edema: • Accumulation
10,000 ft) • Symptoms ... • Signs/Symptoms ... • Signs/Symptoms ... - The classic signs ... • Pathophysiology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
retinal edema caused ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
go on to block blood ... Crises can be precipitated ... The underlying pathophysiology ... Crisis #Features #Signs ... #Symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Decr delivery of blood ... Livedo reticularis Blood ... inflammation tends to cause ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
hyalinization causes ... #Retinopathy #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... are not caused ... skin (16-32%): lupus ... Diagnosis #Management #Signs ... #Symptoms
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