22 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... Motor dysfunction: myoclonic ... incontinence, apraxia ... AlzheimersDisease #Dementia #pathophysiology ... diagnosis #signs #symptoms
Wolff–Parkinson–White syndrome (WPW) is one of several disorders of the electrical system of the heart that
Wolff–Parkinson–White syndrome ... WPW is caused by ... pathway between the atria ... #Pathophysiology ... #Diagnosis #Cardiology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Fits, Hemiplegia, Ataxia ... Demyelinating syndromes ... Glomerulonephritis Myositis(5%) Blood ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Dehydration • Symptoms ... : • Pathophysiology ... diagnosis #management #hematology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... Physiologic Causes ... Acute Coronary Syndrome ... Differential #Diagnosis #Pathophysiology ... #causes #cardiology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... age 70 years Symptoms ... skin that are caused ... Out Secondary Causes ... #diagnosis #hematology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Manifestations Causes ... increase venous blood ... Ophthalmoplegia - Ataxia ... vascular contraction, blood ... beriberi #nutrition #pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
of high parity blood ... donor • Pathophysiology ... without other cause ... ARDS to explain symptoms ... transfusion • Pathophysiology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... -> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology