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diagnosis differential management oncology signs anemia neurology algorithm hepatology treatment disorders vasculitis classification dementia dermatology eosinophilia erythematosus hepatopulmonary leukemia lupus
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
mutations - Down syndrome ... Motor dysfunction: myoclonic ... incontinence, apraxia ... AlzheimersDisease #Dementia #pathophysiology ... diagnosis #signs #symptoms
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Fits, Hemiplegia, Ataxia ... Demyelinating syndromes ... Glomerulonephritis Myositis(5%) Blood ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Cardiovascular Causes ... Water - Pus - Blood ... Hepatopulmonary syndrome ... Other Causes ... Transverse myelitis • Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... plateletcount), peripheral blood ... pylori test (GI symptoms ... or if a primary hematologic ... #Workup #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... workup for specific symptoms ... for secondary causes ... eosinophilia (common causes ... Differential #diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Dehydration • Symptoms ... : • Pathophysiology ... diagnosis #management #hematology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
hemorrhagic rash; symptoms ... CNS and hematologic ... disseminates in blood ... fetal blood vessel ... peds #pediatrics #pathophysiology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
of high parity blood ... donor • Pathophysiology ... without other cause ... ARDS to explain symptoms ... Transfusion #Reactions #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... age 70 years Symptoms ... skin that are caused ... Out Secondary Causes ... #diagnosis #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology
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