37 results
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Pigmentations - Hypopigmentation ... and Hyperpigmentation ... HYPERPIGMENTATION ... Congenital melanocytic nevi ... #Hyperpigmentation
Physiologic Skin Changes in Pregnancy - Differential Diagnosis Algorithm

Face
 • Melasma
Abdomen
 • Linea Nigra 
Hormone induced
Hormone induced • Hyperpigmentation ... erythema • Spider Nevi
Clinical Examination for Liver and Biliary Diseases
1) Hands: Clubbing, Dupuytren's contracture, Leuconychia, Bruising, Flapping tremor (hepatic
Jaundice, Spider naevi ... Gynaecomastia, Spider naevi
Cutaneous signs of Addison's disease may be a useful clue. Hyperpigmentation especially involves sun-exposed areas and
Hyperpigmentation ... often have patchy hyperpigmentation ... flexural on oral hyperpigmentation
Skin Hypopigmentation - Differential Diagnosis Algorithm

Diffuse Congenital - Generalized hypopigmentation of hair, eyes, skin
 • Phenylketonuria
Skin Hypopigmentation ... - Generalized hypopigmentation ... Post-inflammatory hypopigmentation ... #Hypopigmentation
Generalized Hyperpigmentation Differentials
Use the Mnemonic "no skin SPARED"

Images from dermnet.nz and merckmanuals

Mnemonic from https://www.medscape.com/slideshow/dermatology-mnemonics-6011359#5 #diagnosis #differential
Generalized Hyperpigmentation
Benign and Malignant Nevi

Benign Nevus 
The benign nevus, or common mole, usually appears in the first
and Malignant Nevi ... Several nevi may ... those of atypical nevi ... Atypical nevi are ... Look for atypical nevi
Skin Hyperpigmentation - Differential Diagnosis Algorithm
Diffuse:
 • Tanning
 • Adverse cutaneous drug eruption
 • Addison's disease
Skin Hyperpigmentation ... Congenital melanocytic nevi ... Post-Inflammatory hyperpigmentation ... #Hyperpigmentation
Nevus of Ota on Ocular Exam (Ocular Dermal Melanosis)

Benign melanosis in the distribution of the trigeminal
with associated hyperpigmentation
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Examination: • Skin hyperpigmentation ... Hepatosplenomegaly • Spider nevi