12 results
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic ... C3 positive or negative ... mediated - DAT: IgG negative ... Pathophysiology #diagnosis ... #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... - Differential Diagnosis ... AIHA (7-8%) DAT-negative ... #Autoimmune #Hemolytic ... #Table #hematology
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
in Autoimmune Hemolysis ... DAT Negative Hemolysis ... DAT #Autoimmune #Hemolysis ... #hematology #diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... available for rapid diagnosis ... antiglobulin tests - Negative ... ThromboticThrombocytopenicPurpura #Diagnosis ... #Workup #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... for anti-C3d and negative ... • Compensated hemolysis ... #anemia #hematology ... #diagnosis
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
antigens (often false negative ... (rare), false negatives ... infographic by Nick ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
antigens (often false negative ... (rare), false negatives ... in 650,000 by Nick ... #Transfusions #diagnosis ... #management #hematology
THROMBOELASTOGRAPHY (TEG)
General Principle
• A small cuvette is rotated to simulate sluggish venous flow and stimulate clot
development Nick ... Thromboelastography #Diagnosis ... #Management #CriticalCare ... #Hematology #Interpretation
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Coombs (-) hemolytic ... Thrombosis in vascular beds-renal ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
fires, heating pads ... patches on the face, neck ... #differential #diagnosis ... #dermatology #compared