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Calcific Uremic Arteriolopathy (calciphylaxis) - Hand photo and XRay Based on this image, what is the likely
calciphylaxis) - clinical ... syndrome of arteriolar ... calcification -> tissue necrosis ... Note necrotic lesions ... #photo #XRay #clinical
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
weeks • Typical clinical ... cholestasis, no necrosis ... HELLP Syndrome ... unless massive necrosis ... Patchy/extensive necrosis
Esophageal Necrosis Etiology: - Ischemia and Gastric Outlet Obstruction with GERD may be inciting events - Associated
Esophageal Necrosis ... Stevens-Johnson syndrome ... Necrosis should ... restored to esophagus Clinical ... resolution of necrosis
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
not related to clinical ... Ulcers, distal necrosis ... Hyperviscosity syndrome
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Urticaria • Papulo-necrotic ... reticularis • Necrotic ... • Goodpasture syndrome
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... Cryoglobulinemia Syndrome ... : • Clinical triad ... 20% Sjögren's syndrome ... reticularis & skin necrosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... association • M > F Clinical ... tests in Behcet syndrome ... (Clinical Dx). ... alfa, or tumor necrosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... (90%): Aseptic necrosis ... Demyelinating syndromes
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... Guillain-Barré syndrome ... antisynthetase syndrome ... infiltrate engulfing necrotic ... IU/I • SAMS clinical
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
reactivity (Skin necrosis ... Cryofibrinogenemia Clinical ... ulcers • Skin necrosis ... Diagnosis: • + Clinical ... Antiphospholipid syndrome
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