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Drug-induced renal disorders - The most commonly used nephrotoxic drugs

#Pharmacology #Nephrotoxicity #Drugs #Medications #Most #Common #DrugInduced
Drug-induced renal ... used nephrotoxic drugs ... #Medications #Most ... DrugInduced #Acute #KidneyInjury ... #AKI #Table #List
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... ) - Differential ... C3/C4, Other • ATN ... Medicine @SCVMCMed #AKI ... #Diagnosis #nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... - Differential ... Injury/Necrosis (ATN ... causes #Acute #KidneyInjury ... Diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
) - Differential ... Congestion • Medications ... Infection-mediated, Drug-induced ... POST-Renal AKI ... #Diagnosis #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
) - Differential ... at least 50% Renal ... Sjögren) Post-Renal ... #Acute #KidneyInjury ... #Nephrology #Differential
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
there a dialysis indication ... require urgent nephrology ... obstruction, Nephrotoxic drugs ... etiologies due to ATN ... #Acute #KidneyInjury
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Injury • Pre-Renal ... #DrugInduced #KidneyInjury ... #differential # ... diagnosis #algorithm #nephrology ... #Medications
Secondary causes of Hypertension
 • Medications, Drugs, Chemo: NSAIDS, Steroids, CNI, Alcohol, Cocaine, OCP, Licorice, MAOI,
Hypertension • Medications ... , Drugs, Chemo: ... Anti VEGF agents, TKI ... Pseudoephedrine • Primary Renal ... #Hypertension #differential
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Hypertension - Differential ... hypertension (multi-drug ... resistance) Renal ... Nephritic syndrome • AKI ... #Secondary #Nephrology
Primary and Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Primary (Essential) (95%) - Onset between age
Hypertension - Differential ... Uncontrolled • Drug ... licorice • Medications ... disease - CKD, AKI ... Primary #Secondary #HTN