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diagnosis differential hyperkalemia management algorithm hypokalemia medications pharmacology binders binding comparison diuresis diuretics emergencies encephalopathy excretion hemeonc hyponatremia hypotonic low
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... (K) & magnesium( ... wasting from other causes ... urinary losses: • High ... #nephrology #low
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... magnesium, and ... patients sensitive to high ... #Hyperkalemia #medications ... #pharmacology #table
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
- Tumor lysis syndrome ... Medications 2. ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
- Tumor lysis syndrome ... Medications 2. ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... only if no clear cause ... Elimination (see Table ... STOP offending medications ... #potassium #nephrology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Loop Diuretics; High-Ceiling ... Kidney stones caused ... Tolvaptan) • Treatment ... #Pharmacology #Medications ... #Table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... Monitor potassium ... per day until stable ... Diagnosis #Management #causes ... #treatment #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
algorithm Urine Na+K ... diuresis can be high ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Electrolyte abnormality, Medication ... the underlying cause ... • Treatment of ... • Magnesium correction ... with AEDs until cause
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
K, high Phos, high ... Treat underlying cause ... interventional radiology ... → no immediate treatment ... after CRS) - Treatment
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