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Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... than females Guillain-Barre ... bulbar muscles Guillain-Barre ... #Barre #Syndrome ... #diagnosis #management
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Barre Syndrome ... Features Required for Guillain-Barré ... signs, Cranial nerve ... #Barre #Syndrome ... #neurology #neuropathy
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Tumor • Motor Nerves ... Poliomyelitis, Guillain-Barre ... syndrome, Mononeuritis ... #differential #diagnosis ... #neurology
Algorithm showing a stepwise approach to the assessment and investigation of a possible neuropathy. CIDP, chronic
electromyography; GBS, Guillain-Barré ... syndrome; HNPP, ... palsies; NCS, nerve ... #Diagnosis #Neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... albuminocytologic dissociation ... #Barre #Syndrome ... #diagnosis #management ... #neurology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Hypothyroidism • Medication-induced ... Inflammatory/AI: CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... #differential #diagnosis ... #causes #neurology
Guillain–Barré syndrome (GBS)
(aka: Landry–Guillain–Barré–Strohl syndrome:
	Most common cause of acute flaccid paralysis
	Rapidly progressive ascending paralysis & areflexia
	Autonomic
GuillainBarré syndrome ... (aka: Landry–GuillainBarré–Strohl ... albumin-cytologic dissociation ... Differential diagnosis ... prominent cranial nerve
Monteggia Fracture 
Fracture of proximal ulnar shaft with radial head dislocation. Remember “MUGR” to recall where
with radial head dislocation ... the radial head dislocation ... posterior interosseous nerve ... ), compartment syndrome ... Radiology #XRay #Diagnosis
10 Steps to Managing Guillain-Barre Syndrome:
1️⃣ When to suspect
2️⃣ How to Diagnose
3️⃣ When to admit to
Steps to Managing Guillain-Barre ... Syndrome: 1️⃣ ... suspect 2️⃣ How to Diagnose ... GuillainBarre #Syndrome ... #Management #Neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
compression of nerve ... Differential Diagnosis ... Tethered cord • Guillain-Barre ... #differential #diagnosis ... #causes #neurology