19 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Localization of Renal ... loop of Henle Gitelman ... #Localization #Nephron ... #Defects #Pathophysiology ... #Nephrology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
diarrhea / IBD Renal ... - Familial renal ... syndromes - Gitelman ... Diagnosis #Low #Magnesium ... Classification #Causes #Workup
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Differential Diagnosis Renal ... Bartter syndrome and Gitelman ... transplant, Diuretic ... diagnosis #causes #nephrology ... #magnesium #low
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Low Cl intake, Diuretics ... High Urine Cl-: Diuretics ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
Mechanisms of nephron ... • Increased renal ... activities • Diuretic ... syndrome #Mechanisms #pathophysiology ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Extra-renal Losses ... loss (Diarrhea) Renal ... Loop and thiazide diuretics ... Bartter syndrome, Gitelman ... potassium #low #nephrology
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Differential Diagnosis Algorithm ... Malabsorption RENAL ... > 10g • Loop Diuretics ... nephrocalcinosis (FHHNC) • Gitelman's ... Hypomagnesemia #Magnesium
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Low Cl intake, Diuretics ... High Urine Cl-: Diuretics ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #Nephrology #Causes
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... Algorithm 1) ... mOsm/kg - Implies renal ... , Ingestion Renal ... #Algorithm #nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Diagnosis and Workup ... - fevers • renal ... volume loss - diuretics ... Hypernatremia #Diagnosis #Workup ... #Algorithm #Nephrology