6224 results
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Band neutrophils ... Differential Diagnosis ... counts may delay diagnosis ... #differential #diagnosis ... CBC #hematology #pathophysiology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
cytokine that induces neutrophilic ... phagocytosis - Neutrophils ... vessels inflamed by neutrophilic ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
macrophages, and neutrophils ... mediators and recruits neutrophils ... released from neutrophils ... Classification #Pathophysiology ... #Allergy #Diagnosis
Septic Arthritis: Pathogenesis and clinical findings
Notes:
- Septic Arthritis is typically monoarticular & the knee is involved
/mm3 with >50% neutrophils ... SepticArthritis #pathophysiology ... #diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... hit mechanism of neutrophil ... transfusion • Pathophysiology ... Reactions #hematology #diagnosis
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: ... immune cells: Neutrophils ... Rigors #Bacteremia #Pathophysiology ... InfectiousDiseases #Diagnosis
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Causes of Neutrophilia ... - Increased Neutrophils ... - Differential Diagnosis ... #Increased #Neutrophils ... #Differential #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... acute febrile neutrophilic ... dermatosis Diagnosis ... opacities • Diagnosis ... • Differential Diagnosis
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
Hypersegmented neutrophil ... Dysplastic neutrophils ... Hypersegmented #neutrophils
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... 2000-100,000/µL; neutrophil ... culture used to diagnose ... 2000-100,000/µL; neutrophil ... #rheumatology #Diagnosis