6277 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
macrophages, and neutrophils ... mediators and recruits neutrophils ... released from neutrophils ... Pathophysiology #Allergy #Diagnosis ... #Reactions #Table
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Disorientation, vertigo Diagnostic ... (lymphocytes, neutrophils ... Cold #Urticaria #diagnosis ... rheumatology #comparison #table
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
hit mechanism of neutrophil ... Reactions #hematology #diagnosis ... #comparison #table
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Causes of Neutrophilia ... - Increased Neutrophils ... - Differential Diagnosis ... #Increased #Neutrophils ... #Differential #Diagnosis
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
Hypersegmented neutrophil ... Dysplastic neutrophils ... Hypersegmented #neutrophils
How to distinguish a metamyelocyte from a band neutrophil.

- Kyle Bradley, MD
@KyleBradleyMD

#Clinical #Pathology #Microscopy #Blood #Smear
metamyelocyte from a band neutrophil ... Metamyelocytes #Bands #Neutrophils
Sweet’s Syndrome - Acute febrile neutrophilic dermatosis 

The syndrome involves fever, painful rash, neutrophilic leukocytosis, and
Acute febrile neutrophilic ... painful rash, neutrophilic ... leukocytosis, and neutrophil ... Sweets #Syndrome #neutrophilic
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
granulocytes (neutrophils ... Neutrophil bands ... : Immature neutrophils ... as significant neutrophilia ... Mature neutrophils
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
> 10% Band neutrophils ... Band neutrophils ... Differential Diagnosis ... counts may delay diagnosis ... #differential #diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile neutrophilic ... Neutrophilic dermatoses ... Leukemia cutis Diagnosis ... infiltrate of neutrophils ... Sweet #Syndrome #diagnosis