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diagnosis differential causes rheumatology bleeding dermatology alopecia ana antibodies antinuclear arthritis bruising cryoglobulinemia cryoglobulins dermatitis disease enlarged erythema erythematosus gammopathy
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... lymphadenopathy more diffuse ... involvement, irregular pattern ... #Classification ... pathophysiology #Hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
significant • Pattern ... : The ANA patterns ... • Nucleolar: Diffuse ... Lymphoproliferative Disorders ... #rheumatology #
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Differential Diagnosis Algorithm ... Sequestration Disordered ... Rare • Drugs (e.g ... Disease Vascular System ... #Causes #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Differential Diagnosis Algorithm ... Myeloproliferative disorders ... Inflammatory • Systemic ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... heart disease Systolic ... and obstructive pattern ... multifactorial mechanisms Hematologic ... Systemic disorders
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Traction alopecia Diffuse ... Vitamin D levels Systemic ... Disorders: ... • Hormonal disorder ... Differential #Diagnosis #dermatology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... to Systemic Diseases ... halt nail growth (e.g ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... hematological disorders ... (e.g. systemic ... diagnosis #types #classification ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... . hematologic) ... pneumonitis • Diffuse ... enteropathy, and diffuse
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
• Presence of systemic ... • Unusual pattern ... non-accidental injury Pattern ... connective tissue, e.g ... pediatrics #diagnosis #hematology
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