287 results
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
and Inotropes Norepinephrine ... : Distributive shock ... line for septic shock ... ), Cardiogenic shock ... , Shock where ↑
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
Shock and Vasoactive ... and etiology of shock ... Ino-Constrictors: Norepinephrine ... Nesiritide 3) Treat shock ... #Vasopressors #shock
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
Inotropes • Norepinephrine ... pressor added in shock ... in refractory shock ... in setting of shock ... - Cardiogenic shock
Clinical Management for Three Common Causes of Shock 
HEMORRHAGIC SHOCK
 • Ensure adequate ventilation and oxygenation.
Common Causes of Shock ... HEMORRHAGIC SHOCK ... CARDIOGENIC SHOCK ... inotropic support; norepinephrine ... vasopressor support with norepinephrine
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
and Inotropes Norepinephrine ... pharmacology #comparison #shock
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
increased MAP Norepinephrine ... first agent in shock ... line in septic shock
Systemic Inflammatory Response Syndrome (SIRS)
•	Non-specific (infections vs non-infectious)
•	≥2 of the following:
o	Temp >38°C or <36°C
o	HR >90 bpm
o	RR
Septic Shock • ... Vasopressors (norepinephrine ... #sepsis #sirs #shock
Severe Heart Failure & Cardiogenic Shock - Management Checklist 
Evaluation 
 - EKG & echocardiography
& Cardiogenic Shock ... function tests if shock ... organ dysfunction) Norepinephrine ... with cardiogenic shock ... Checklist #CHF #Shock
Pediatric Trauma Primary Survey: C-ABCDE
C - Catastrophic Bleeding - Life-threatening hemorrhage
 • Apply direct pressure/compression bandage
- Hemorrhagic shock ... a late sign of shock ... signs Neurogenic shock ... maintain BP: - NORepinephrine
Cardiovascular effects of intravenous infusion of Epinephrine, Norepinephrine and Isoproterenol

#Epinephrine #Norepinephrine #Isoproterenol #Pharmacology #Cardiovascular #Effects #Pathophysiology
of Epinephrine, Norepinephrine ... #Epinephrine #Norepinephrine