889 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
IGFIR activates osteoblasts ... GrowthHormone #GH #FeedbackLoop
Bone resorption and the relationship between osteoblasts and osteoclasts.  
RANK is expressed on the osteoclasts,
relationship between osteoblasts ... marrow cells and osteoblasts ... RANK stimulates osteoclast ... projections from an osteoclast ... lysosomes in the osteoclast
Rheumatoid Arthritis
Rheumatoid Arthritis (RA) is an inflammatory autoimmune condition. While chiefly thought of as a joint
inflammation #joint #msk ... TNF #CRP #RANKL #ostoblast
Feedback Loop: Prolactin (PRL)
 • PRL levels exhibit diurnal, menstrual, and age-related variation
 • TRH has
Prolactin #PRL #FeedbackLoop
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
cartilaginous matrix by osteoblasts ... mos - yrs) • Osteoclast-osteoblast ... gentamycin - Toxic to osteoblasts ... #Orthopedics #msk
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings

 • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
production of osteoblasts ... and GF's -> Osteoblasts
Hand Arthritides - Differential Diagnosis by Location and Features

The Painful Hand!  Wish I would’ve thought
prior to my first MSK ... Diagnosis #Location #MSK
Radius and Ulna Anatomy

By @rev.med

#Radius #Ulna #Anatomy #Bones #orthopedics #MSK
#orthopedics #MSK
Humerus Bony Anatomy - Anterior and Posterior Views

By @rev.med

#Humerus #Bony #Anatomy #MSK #Bone
Bony #Anatomy #MSK
Medial Thigh Muscles Anatomy

By @rev.med

#Medial #Thigh #Muscles #Anatomy #MSK #orthopedics
Muscles #Anatomy #MSK