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diagnosis differential oncology algorithm causes dermatology hepatology management rheumatology systemic aplastic cancer classification generalized hemolytic injury leukemia liver mds monoclonal
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia Fanconi Anemia Acquired Aplastic Anemia Dyskeratosis Congenita & Telemore Biology
Marrow Failure Syndromes ... Congenita & Telemore Biology ... Shwachman-Diamond Syndrome ... #Pancytopenia #Syndromes ... #diagnosis #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Iron-deficiency anemia ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... #differential #hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... proportion of the red blood ... The etiology of ... Pancytopenia is a hematologic ... three peripheral blood
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... • Aplastic Anemia ... Megaloblastic Anemia ... #diagnosis #hematology ... #oncology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... disease, Acute blood ... loss, Anemia of ... Myelodysplastic syndrome ... diagnosis #causes #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... vasculitis • Hematologic ... Abnormalities: macrocytic anemia ... criteria for 1) hematologic ... including peripheral blood
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... result from low blood ... #oncology #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... : Acute blood loss ... hemolysis, deficiency anemia ... Kawasaki, Nephrotic syndrome
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... Management #treatment #hematology ... #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Algorithm Normal Blood ... • Pernicious Anemia ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
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