265 results
Acetaminophen toxicity
Emergency Department Workup and Management - Rumack Matthew Nomogram

#Diagnosis #Management #Toxicology #APAP #Acetaminophen #Rumack #Nomogram
Acetaminophen toxicity ... Management #Toxicology #APAP ... Nomogram #Stages #Toxicity ... #Overdose
Acetaminophen metabolism and factors affecting toxicity. 
GSH = glutathione 

#Acetaminophen #APAP #metabolism #toxicity #Toxicology #Pathophysiology #Overdose
factors affecting toxicity ... Acetaminophen #APAP ... #metabolism #toxicity ... Pathophysiology #Overdose
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
non-toxic route of APAP ... gets saturated in overdoses ... Toxicology #NAC #APAP ... Acetaminophen #Toxicity
N-Acetylcysteine (NAC) restores hepatic glutathione!
Found to have 21-28% reduction in mortality for acetaminophen-induced hepatic failure
The earlier
concern for ANY overdose ... Acetaminophen #Toxicity ... #APAP
Acetaminophen Intoxication Algorithm

- Dr. Josh Farkas @PulmCrit

#Acetaminophen #Algorithm #Toxicology #Overdose #Algorithm #Management #APAP #Overdose #Tylenol
Algorithm #Toxicology #Overdose ... Algorithm #Management #APAP ... #Overdose #Tylenol
Noninvasive Positive Pressure Ventilation (NIPPV)

Expiratory & Inspiratory Positive Airway Pressure
Both increase intrathoracic pressure, which can decrease
EPAP prevents upper ... CPAP - Continuous ... and mortality BPAP ... Provides both EPAP ... and IPAP.
BiPAP titration in CHF
 - Mean airway pressure provides goodness 
 - Ramp up the ePAP
- Ramp up the ePAP ... Could also use CPAP ... breathing (equal to iPAP-ePAP ... - Ramp up iPAP
Aspirin (Salicylate) Overdose and Toxicity

#Aspirin #Salicylate #Overdose #Toxicity #Pathophysiology #Diagnosis
Aspirin (Salicylate) Overdose ... and Toxicity ... Aspirin #Salicylate #Overdose ... #Toxicity #Pathophysiology
Beta-Blocker Overdose/toxicity:

•	Bradycardia & hypotension (most common).
•	Myocardial depression & cardiogenic shock (severe overdoses). 
•	Ventricular dysrhythmias (Common with
Beta-Blocker Overdose ... /toxicity: • ... shock (severe overdoses ... • Delayed toxicity ... #toxicity #poisoning
Pharmacology, Toxicity and Management of Second Generation Antipsychotic (SGA) Overdose #Diagnosis #Management #Toxicology #Psychiatry #SGA #SecondGenerationAntipsychotics
Pharmacology, Toxicity ... Antipsychotic (SGA) Overdose ... SecondGenerationAntipsychotics #Overdose