601 results
The Cell Cycle
The cell cycle is the series of tightly regulated steps that controls cell growth
Both Rb and p53 ... Thats right, p53 ... is too great, p53 ... Yes, its p53 (and ... proteins) that cause
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
associated with PR3 ... involvement - PR3 ... 75-90%, rarely PR3 ... disease - MPO>PR3 ... + almost 100%, PR3
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
polyangiitis - MPO>PR3 ... polyangiitis - PR3 ... involvement - PR3 ... Churg-Strauss) - MPO>PR3 ... disease - MPO>PR3
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Negative IF): • PR3 ... differential #diagnosis #algorithm
Causes of Hypercalcemia due to increased Vitamin D levels
 • The BIG 3:
Causes of Hypercalcemia ... granulomatous diseases: PR3 ... Hypercalcemia #VitaminD #causes
Causes of Nausea and Vomiting - Differential Algorithm #Diagnosis #EM #IM #Causes #Nausea #Vomiting #Differential #NonGI
Causes of Nausea ... - Differential Algorithm ... Diagnosis #EM #IM #Causes ... #Nausea #Vomiting ... Differential #NonGI #Algorithm
Causes of Acute Kidney Injury - Differential Diagnosis Framework 
Pre-Renal
Post-Renal
Intrinsic Renal:
 • Tubules (ATN)
 • Glomerular:
Causes of Acute ... Diagnosis Framework Pre-Renal ... #KidneyInjury #Causes ... Differential #Diagnosis #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
proteinase 3 (PR3 ... in >90%, MPO > PR3 ... Granulomas - MPO > PR3 ... 80% (80-90% have PR3 ... proteinase 3 (PR3
Hypertension in Pregnancy - Differential Diagnosis Algorithm

Pre-existing Hypertension - Before Pregnancy OR <20 weeks gestational age
Differential Diagnosis Algorithm ... Pre-existing ... • Pre-Eclampsia ... Differential #Diagnosis #Algorithm ... #causes #obstetrics
Causes of Female and Male Infertility - Differential Diagnosis Algorithm
Causes of Female Infertility:
 • Uterus -
Causes of Female ... Differential Diagnosis Algorithm ... Causes of Female ... semen analysis • Pre-Testicular ... Differential #Diagnosis #Algorithm