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Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
Kidney Injury (AKI ... ATN - 45% - Pre-renal ... disease — 21% - AKI ... mostly ATN and pre-renal ... Nephrology #Diagnosis #Algorithm
Causes of Acute Kidney Injury - Differential Diagnosis Framework 
Pre-Renal
Post-Renal
Intrinsic Renal:
 • Tubules (ATN)
 • Glomerular:
Diagnosis Framework Pre-Renal ... drtonydang @CMC_IM #AKI ... Differential #Diagnosis #Algorithm
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... Diagnosis Framework Pre-Renal ... Medicine @SCVMCMed #AKI ... nephrology #causes #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
proteinase 3 (PR3 ... in >90%, MPO > PR3 ... Granulomas - MPO > PR3 ... 80% (80-90% have PR3 ... proteinase 3 (PR3
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Negative IF): • PR3 ... differential #diagnosis #algorithm
Subtypes of Serum Proteins

Pre-albumin (Transthyretin)
Albumin
Globulins
 • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
Serum Proteins Pre-albumin ... Proteins #Subtypes #algorithm ... #classification
Atrioventricular Blocks (AV blocks) - ECG Diagnosis Summary
First Degree AV Block
 • The P wave is
AV Block Type I aka ... Block type II (aka ... High-grade AV Block aka ... Degree AV Block aka ... electrocardiogram #classification
Summary of Heart Blocks
1st Degree Heart Block:
 • Prolonged PR >200ms (5 small squares).
 • Narrow
• Prolonged PR ... I Heart Block (aka ... • Prolonged PR ... PR shorted after ... HeartBlocks #Types #Classification
HSCT related renal disease - AKI and CKD
Acute Kidney Injury: Acute GvHD 2-4, Pre renal state,
renal disease - AKI ... Acute GvHD 2-4, Pre ... renal #disease #AKI ... differential #diagnosis #algorithm