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Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
gap acidosis (pH ... • Euglycemic DKA ... • DKA/HHS Overlap ... features of both DKA ... Disorders #ketones #differential
Ketosis Disorders - Comparison Table • Starvation Ketosis • Alcoholic Ketoacidosis (AKA) • Diabetic Ketoacidosis (DKA)
Ketoacidosis (AKA ... Ketoacidosis (DKA ... • Euglycemic DKA ... State (HHS) • DKA ... Disorders #ketones #differential
Hyperglycemic Crisis - Algorithm for DKA/HHS Diagnostic criteria for DKA: • pH < 7.3 • Anion gap
Algorithm for DKA ... Diagnostic criteria for DKA ... : • pH < 7.3 ... criteria for HHS: • pH ... MatthewHoMD #DKA
Diabetic Ketoacidosis (DKA) - Diagnosis and Management Summary Symptoms: • Abdominal pain • Nausea • Polyuria • Polydipsia • Vomiting • Weight loss •
Ketoacidosis (DKA ... , and death DKA ... > 18 mEq/L 2) pH ... 200 mg/dL #DKA
DKA DIAGNOSTIC CRITERIA: 1. Serum glucose >250 mg/dL 2. Arterial pH <7.3 3. Serum bicarbonate <18 mEq/L 4. At least
DKA DIAGNOSTIC CRITERIA ... Arterial pH <7.3 ... 10% to 30% of DKA ... Patients with DKA ... #DKA #EDKA #Insulin
SGLT2 Inhibitors and Euglycemic DKA Risk factors for euglycemic DKA in those on an SGLT2i include: •
and Euglycemic DKA ... for euglycemic DKA ... include: • Serum pH ... SGLT2 #Euglycemic #DKA ... #EDKA #Toxicity
Diabetic Ketoacidosis (DKA) - Diagnosis and Management Summary Symptoms: • Abdominal pain • Nausea • Polyuria • Polydipsia • Vomiting • Weight loss •
Ketoacidosis (DKA ... , and death DKA ... > 18 mEq/L 2) pH ... 200 mg/dL #DKA
Renal Tubular Acidosis - Differential Diagnosis Algorithm Decreased Serum K, Urine pH < 5.5 - Proximal RTA Decreased
Tubular Acidosis - Differential ... Serum K, Urine pH ... Serum K, Urine pH ... Acidosis • Urine pH ... Tubular #Acidosis #Differential
"Eight I's" mnemonic for the main causes of hyperglycemia. #hhs #dka #ketoacidosis #diabetes #diabetic #em #differential
#hhs #dka #ketoacidosis ... #diabetic #em #differential
Pathophysiology of Tumor Lysis Syndrome (TLS) Tumor Cell Lysis -> Release of DNA • Purines -> Hypoxanthine /
-> Release of DNA ... Nephropathy (low urine pH ... nephropathy (high urine pH
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