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diagnosis management differential endocrinology toxicology treatment comparison nephrology pharmacology clinical diabetic diabeticketoacidosis edka im ketoacidosis rhabdomyolysis toxicity abscess acidosis agents
DKA DIAGNOSTIC CRITERIA: 1. Serum glucose >250 mg/dL 2. Arterial pH <7.3 3. Serum bicarbonate <18 mEq/L 4. At least
Arterial pH <7.3 ... cases occur in ... ketoacidosis include nausea ... the anion gap closes ... #DKA #EDKA #Insulin
Diabetic Ketoacidosis (DKA) - Diagnosis and Management Summary Symptoms: • Abdominal pain • Nausea • Polyuria • Polydipsia • Vomiting • Weight loss •
Ketoacidosis (DKA ... Abdominal pain • Nausea ... , and death DKA ... > 18 mEq/L 2) pH ... 200 mg/dL #DKA
SGLT2 Inhibitors and Euglycemic DKA Risk factors for euglycemic DKA in those on an SGLT2i include: •
and Euglycemic DKA ... for euglycemic DKA ... include: • Serum pH ... therapy in severe cases ... SGLT2 #Euglycemic #DKA
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
ketoacidosis (DKA ... ) - caused by complete ... gap acidosis (pH ... • Euglycemic DKA ... Glucosuria causes
Diabetic Ketoacidosis (DKA) - Diagnosis and Management Summary Symptoms: • Abdominal pain • Nausea • Polyuria • Polydipsia • Vomiting • Weight loss •
Ketoacidosis (DKA ... Abdominal pain • Nausea ... , and death DKA ... > 18 mEq/L 2) pH ... 200 mg/dL #DKA
Pathophysiology of Tumor Lysis Syndrome (TLS) Tumor Cell Lysis -> Release of DNA • Purines -> Hypoxanthine /
Pathophysiology ... -> Release of DNA ... Nephropathy (low urine pH ... nephropathy (high urine pH ... Syndrome #TLS #Pathophysiology
Renal tubular acidosis (RTA): refers to a group of conditions all of which cause the same
conditions all of which cause ... different types/causes ... RenalTubularAcidosis #Features #Table ... #Comparison #PH
Pathyophysiology - hyperglycemic crises in patients with diabetes Key signs/symptoms of HHS/DKA: Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... hyperglycemic crises ... symptoms of HHS/DKA ... , hypotension) DKA ... #EM #IM #Endo #DKA
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... Findings • Note: in DKA ... out of cells may cause ... Treating DKA: 1) ... #pathophysiology
Salicylate Toxicity - Diagnosis and Management Consider if: 1) Patient is hot and altered 2) You see tachypnea with
no respiratory cause ... Presentation seems like DKA ... exposure Symptoms: Nausea ... Resuscitation 2) Urine pH
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