13 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... Angiotensin-converting enzyme (ACE ... Heparin) • Sodium-channel ... • Increased EC ... #pharmacology #potassium
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... • Mechanism: Exchanges ... increase dose as ... of aspiration #Potassium ... #pharmacology #table
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ... ECG changes, weakness ... changes? ... treatment Remove potassium
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... Algorithm • IV ... Dialysis Serum potassium ... and ECG changes ... #potassium #high
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
Hyperkalemia shortens ... repolarization; changes ... #Diagnosis #Hyperkalemia ... #EKG #ECG #Changes ... #Progression #Table
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• NSAIDs • ACE ... • Recent IV potassium ... kiwis, mangoes, oranges ... differential #diagnosis #causes ... #potassium #high
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
eliminate excess potassium ... reduce dietary potassium ... , changes on ECG ... Figure 3 is an algorithm ... , and Table 3 summarizes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• NSAIDs • ACE ... • Recent IV potassium ... kiwis, mangoes, oranges ... differential #diagnosis #causes ... #potassium #high
Acute Coronary Syndrome (ACS) Definitions - Stable Angina, Unstable Angina, NSTEMI, STEMI
1 STABLE ANGINA - Angina
Coronary Syndrome (ACS ... thrombus formation causes ... is reflected by ECG ... changes and a rise ... Diagnosis #Cardiology #ACS
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
heparinized tube) • ECG ... only if no clear cause ... Elimination (see Table ... K-Binding Resins - Exchanges ... Management #Treatment #potassium