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diagnosis differential algorithm coagulation syndrome abnormal anemia disorders pt treatment elevatedmcv eosinophilia lupus macrocytosis oncology product reactions sle transfusion workup
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Artifactually Prolonged ... to identify the cause ... of Prolonged APTT ... #prolonged #diagnosis ... #hematology #evaluation
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PTT • Prolonged ... PTT • Prolonged ... Diagnosis #Algorithm #Causes ... #Hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... Pre-analytical cause ... #Prolonged #Causes ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and aPTT If ... the PT and the aPTT ... are both prolonged ... #Prolonged #Causes ... #differential #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
is prolonged, but ... mixing study (aPTT ... normal in mild cases ... hemophilia type (e.g ... #treatment #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
plateletcount), peripheral blood ... : INR/PT, aPTT(liver ... function test, ANA (e.g ... or if a primary hematologic ... #Workup #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... Thrombocytopenia • Prolonged ... Treat primary cause ... #treatment #management ... #hematology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
intake) • Target blood ... Insufficient blood ... (e.g. renal failure ... Measurement #SLE #rheumatology ... levels #lupus #management
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Iron Deficiency (Eg ... Causes: Chronic ... Blood Loss, Occult ... #Hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... for secondary causes ... eosinophilia (common causes ... signs or symptoms (eg ... Differential #diagnosis #hematology
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