12 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
the PT or APTT ... to identify the cause ... of Prolonged APTT ... #APTT #prolonged ... #diagnosis #hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... PTT, Normal PT ... PTT, Normal PT ... Differential #Diagnosis ... #Hematology #coagulation
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Investigation of Abnormal ... PT - Prolonged ... aPTT and Prolonged ... PT - Prolonged ... #Hematology #Diagnosis
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... #PT #aPTT #Prolonged ... #Causes #diagnosis ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
PT and aPTT If ... aPTT are both prolonged ... #PT #aPTT #Prolonged ... #Causes #diagnosis ... #differential #hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
bleeding • Prolonged ... PT/INR • Normal ... aPTT (prolonged ... VonWillebrand #Disease #Diagnosis ... #Hematology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Plasma → Recheck abnormal ... PT and/or aPTT) ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
is prolonged, but ... mild cases) • ... PT/INR & von Willebrand ... hemophilia type (e.g ... Management #treatment #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... : INR/PT, aPTT(liver ... function test, ANA (e.g ... #Differential #Diagnosis ... #hematology