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diagnosis differential management treatment high medications aldosterone algorithm angiotensin comparison criticalcare crystalloids diuresis diuretics druginduced effects encephalopathy excretion foamed hematology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC ... Benyzlpenicillin, blood ... pathophysiology #pharmacology ... #potassium #medications
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... wasting from other causes ... losses: • High Blood ... • Low/Normal Blood ... #nephrology #low
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS) This is a very common pathway that clinicians should
sodium, which causes ... increased blood ... This decreases blood ... avoid harmful hyperkalemia ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Crush injury • Blood ... Blood transfusion ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Crush injury • Blood ... Blood transfusion ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... UA positive for blood ... Monitor potassium ... Diagnosis #Management #causes ... #treatment #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... heparinized tube) • ECG ... only if no clear cause ... Management #Treatment #potassium ... #nephrology #K
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
130 mEq/L • Potassium ... Is Dangerous in Hyperkalemia ... shift • Saline Causes ... • Saline May Cause ... NS #comparison #pharmacology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Hyponatremia • Hypercalcemia ... Kidney stones caused ... Prevention of blood ... Excretion #Diuresis #Nephrology ... #Pharmacology #
The crusade against “Ab”Normal Saline continues. This is a non-physiologic fluid that can harm our
The ECF and ICF ... causes Hyperkalemia ... reduces renal blood ... reduced renal blood ... diagnosis #treatment #pharmacology
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